How to temporarily disable mouse device?

I have wireless USB keyboard and mouse combo.

I need a way to disable mouse while leaving keyboard function working and a way to enable it again after some time.

I don't use X and I can't make it in desktop space as I use plain EGL, so it has to be done deeper, I guess in kernel space.

I tried to play with /sys/bus/usb/* stuff and I managed only to disable whole USB device, but that wasn't what I need as both keyboard and mouse were disabled.

Any ideas?